Pb concentration was almost twice as high in RTRs who used tacrolimus with mycophenolate mofetil than in RTRs who used cyclosporine A with mycophenolate mofetil. This value was significantly higher than in ex-smokers (, The assessment of welfare in aquatic animals is currently under debate, especially concerning those kept by humans. Multivariate analysis was used to detect phenotypic and genetic variations of wheat genotypes more closely under salinity stress, and we analyzed how these strategies effectively balance each other. Scientifically, we encounter an evolution of technology in today’s world of biology and medical-research. Additionally, we analyzed the effect of selected biological and environmental factors, including the intake of various immunosuppressive drug regimens and smoking, on these xenobiotic concentrations. Most clinical studies have been focused on the impact of dietary intake or supplementation with mixtures of compounds, with only a few addressing the effect of isolated compounds. Isoflavones are phytoestrogen compounds with important biological activities, including improvement of cardiovascular health. This review highlights the role of connexin mediated communication in avascular epithelial tissue. The journal encourages the submission of multidisciplinary studies that use complementary experimental and computational … Shear exposure did not affect reactive species in the sub-populations but reduced RBC nitric oxide synthase (NOS) activation and intriguingly increased RBC deformability in old RBCs. While methods for evaluating their emotions (such as fear, pain, and anguish) are currently being developed for aquatic species and understanding the natural behavior of all aquatic taxa that interact with humans is a task that requires more time, the evaluation of internal responses in the organisms can be carried out using analytical tools. A multiple linear regression model and path coefficient analysis showed a coefficient of determination (R, The gut–liver-axis is a bidirectional coordination between the gut, including microbial residents, the gut microbiota, from one side and the liver on the other side. Add your e-mail address to receive forthcoming issues of this journal: The statements, opinions and data contained in the journal, © 1996-2021 MDPI (Basel, Switzerland) unless otherwise stated. Given that blood contains RBCs with non-uniform physical properties, whether all. Introduction. The journal ‘Biology and Medicine’ publishes the current research activities in this growing field of medicine. Equal concentrations of Cd were found in erythrocytes of both female and male transplant recipients. The fused journal will maintain and build on the strengths of both journals, publishing high-quality research across all of biology, as well as authoritative and topical review and comment. JLB is a peer-reviewed, academic journal published by the Society for Leukocyte Biology for its members and the community of immunobiologists. The journal publishes original papers at the forefront of Agriculture, Biology and Healthcare research. Factors such as the special distribution of the intermediate filaments in each layer (dorsal, intermediate, and ventral), the relative thickness of the layers, and their chemical composition define the characteristics of each, The nail plate is made up of tightly packed keratin-rich cells. Red blood cell (RBC) deformability is an essential component of microcirculatory function that appears to be enhanced by physiological shear stress, while being negatively affected by supraphysiological shears and/or free radical exposure. Productivity can be enhanced using salt-tolerant wheat genotypes. Outputs of NO generation appeared dependent on cell age; in general, stressors applied to younger RBCs tended to induce S-nitrosylation of RBC cytoskeletal proteins, while older RBCs tended to reflect markers of nitrosative stress. The classic concept of animal welfare includes three elements: The emotional state of the organism (including the absence of negative experiences), the possibility of expressing normal behaviors, and the proper functioning of the organism. However, the detailed mechanism remains elusive. Does KRAS Play a Role in the Regulation of Colon Cancer Cells-Derived Exosomes? Atomic force. Open Access —free for readers, with article processing charges (APC) paid by authors or their institutions. Principle component analysis detection of the first two components explains 70.78% of the overall variation of all traits (28 out of 32 traits). Since the classical methods of assessing welfare are laborious and time-consuming by evaluation of fear, pain, and anguish, the assessment may be complemented by physiological approaches. By using this website, you agree to our The online version is free access and download. The fused journal will maintain and build on the strengths of both journals, publishing high-quality research across all of biology, as well as authoritative and topical review and comment. View Collections Elemental composition was analysed in each layer using scanning SEM-EDS, and nail plate thickness was measured by image analysis. Any disturbance in this crosstalk may lead to a disease status that impacts the functionality of both the gut and the liver. However, the assessment of salt tolerance potential in bread wheat doubled haploid lines (DHL) through agro-physiological traits and stress-related gene expression analysis could potentially, Salinity majorly hinders horizontal and vertical expansion in worldwide wheat production. When the exosomal proteins of SW480 cells were profiled, a total of 435 proteins were identified with 16 of them showing significant changes (greater than or equal to two-fold) in response to FTS treatment. The International Journal of Developmental Biology is a peer-reviewed open access scientific journal covering research in developmental biology.The current editor-in-chief is Juan Arechaga (University of the Basque Country). Guest Editors: Inna Khozin-Goldberg, Dina Zilberg, Alexei Solovchenko, Guest Editors: Natalia Osna, Valentina Medici, Kusum K. Kharbanda, Guest Editors: Raghubendra S. Dagur, Natalia Osna, Guoku Hu, Guest Editors: Nils-Kåre Birkeland, Yoshizumi Ishino, Help us to further improve by taking part in this short 5 minute survey, A Tangled Threesome: Circadian Rhythm, Body Temperature Variations, and the Immune System, Circadian Disruption and Metabolic Disorders, A Universal Model for the Log-Normal Distribution of Elasticity in Polymeric Gels and Its Relevance to Mechanical Signature of Biological Tissues, Analysis of Cadmium, Mercury, and Lead Concentrations in Erythrocytes of Renal Transplant Recipients from Northwestern Poland, Physiology: An Important Tool to Assess the Welfare of Aquatic Animals, Connexins and the Epithelial Tissue Barrier: A Focus on Connexin 26. Following this, we discuss the relevance of this model for mechanical signatures of biological tissues. To understand the interaction between cells and their surrounding extracellular matrix, the characterization of the mechanical properties of natural polymeric gels is needed. The nail plate is made up of tightly packed keratin-rich cells. The increasingly frequent cutaneous manifestations of coronavirus disease (COVID-19) remain to pose a problem to clinicians. The Yale Journal of Biology and Medicine is a PubMed-indexed, open access, quarterly journal edited by Yale medical, graduate, and professional students and peer reviewed by an extensive network of experts in the fields of biology and medicine. California Privacy Statement, Additionally, we highlight the contribution of gut microbiota to the metabolism of antivirals used in HCV treatment regimens and the impact of these medications on the microbiota composition. 1. read the Aims & Scopeto gain an overview and assess if your manuscript is suitable for this journal; 2. use the Microsoft Word template or LaTeX templateto prepare your manuscript; 3. make sure that issues about publication ethics, research ethics, copyright, authorship, figure formats, data and references formathave been appropriately considered; 4. ensure that all authors have approved the content of the submitted manuscript. There is nowadays growing evidence on the role of the temperature circadian rhythm on the expression of the molecular clock. Red blood cell (RBC) deformability is an essential component of microcirculatory function that appears to be enhanced by physiological shear stress, while being negatively affected by supraphysiological shears and/or free radical exposure. The classic concept of animal welfare includes three elements: The emotional state of the organism (including the absence of negative experiences), the possibility of expressing normal. The functional consequences of dysregulated connexin activity is discussed and the development of connexin targeted therapeutic strategies highlighted. This review sheds light on the potential of the gut microbiota manipulation as an alternative therapeutic approach to control the liver complications post HCV infection. Herein, we aimed to describe the clinical and pathological findings of skin lesions in patients with COVID-19. Please. The highest level of Cd was seen in smokers, who had 3.25 µg/L. In addition, a high level of acetyl-coA synthetase family member 4 protein which plays an important role in colon cancer survival was identified in the exosomes secreted by FTS-treated SW480 cells. To understand the interaction between cells and their surrounding extracellular matrix, the characterization of the mechanical properties of natural polymeric gels is needed. The journal publishes original scientific research papers that provide mechanistic and functional insights and report a significant advance to the field. The structure of the first toe is independent of that of the other toes, while the functional difference remains unclear. We observed that FTS inhibits KRAS activity in SW480 cells, but promotes their exosome production. This includes studies of their responses to these effects and on the ecological consequences. A total of 12 elements were detected in nail plates, of which carbon, nitrogen, phosphorus, sulphur, and calcium showed significant differences between layers (, Recent studies suggested that the fraction of CG dinucleotides (CpG) is severely reduced in the genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The main objective of this study is to determine nail consistency by calculating a predictive model based on elemental composition analysis using scanning electron microscopy. When the MTPJ was dorsiflexed at 0°, 15°, and 30°, the MVC torque of the first MTPJ when the ankle was dorsiflexed at 20° was higher than that when the ankle was plantar-flexed at 20°. The aim of this study is to determine the blood erythrocyte concentrations of toxic metals (Cd, Pb, and Hg) in renal transplant recipients (RTRs). The Year in Cell Biology: 2020 We are delighted to present this collection of cutting-edge research published over the past year in the Journal of Cell Biology . These results suggest that AChRe may be a regulator of mammalian sperm AR. Springer Nature. The purpose of this study was to investigate the difference in the force generation characteristics between the plantar-flexion of the first and second–fifth metatarsophalangeal joints (MTPJs) by comparing the maximal voluntary plantar-flexion torques (MVC torque) at different MTPJs and ankle positions. Privacy Cd, Hg, and Pb levels in the erythrocytes were quantified by inductively coupled mass spectroscopy (ICP-MS). PMS increased total free radicals in both sub-populations, and RBC deformability decreased accordingly. It appears that the elasticity (elastic modulus) values obtained by AFM presents a log-normal distribution. This is a list of articles about scientific journals in biology aund its various ''''' subfields. SCIREA Journal of Biology is an international, scientific peer-reviewed open access journal published online by SCIREA. IISTE is a member of CrossRef. Much research has been conducted on the concentrations of heavy metals, microelements, and macroelements in the blood, but little is known about the concentration of Cd, Pb, and Hg in erythrocytes of renal recipients. The superfamily is dominated by two similarly sized families, Braconidae and Ichneumonidae, which are collectively divided into approximately 80 subfamilies. Preferably, papers should test hypotheses or explore new grounds. Polydnaviruses infect and have profound effects on host physiology in conjunction with various venom and ovarial secretions, and have attracted an immense amount of research interest. The mechanosensitivity of cells has recently been identified as a process that could greatly influence a cell’s fate. We thus present novel findings pertaining to the interplay of mechanical stress and redox metabolism in circulating RBC sub-populations. Please note that many of the page functionalities won't work as expected without javascript enabled. The nicotinic acetylcholine receptor (nAChR) is one of the receptors of acetylcholine (ACh), and nicotine (NIC) acts as an agonist of this receptor. Therefore, our findings indicate that a febrile rash or even a rash in an afebrile state in the early stages of the disease may be the only clinical manifestation of COVID-19. This paper highlights isolated isoflavones as potentially suitable alternatives to soy-based foodstuffs and supplements and which could enlarge the current therapeutic arsenal. Welcome to the Journal of Biology and Medical-Research. Exosomes are cell-derived nanovesicles, and lately, cancer-derived exosomes have been reported to carry KRAS protein, which contributes to the malignancy of many cancers. This paper reviews the main actions of isolated isoflavones on the vasculature, with particular focus given to their effect on the determinants of blood pressure regulation. MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. This tissue is also highly accessible for therapeutic targeting. Journal of Biology has now been fused with BMC Biology under the title BMC Biology. However, the ankle position had no significant effect on the MVC torque of the second–fifth MTPJ. Nonetheless, more studies are needed to better establish their safety profile and elect the most useful applications. The very large wasp superfamily Ichneumonoidea is composed of parasitoids. Also, it seeks scientists relating the structure and dynamics of living organisms with their physiology and phenotypic traits for the understanding of the whole. This activity is most evident in populations with a high isoflavone dietary intake, essentially from soybean-based products. The nicotinic acetylcholine receptor (nAChR) is one of the receptors of acetylcholine (ACh), and nicotine (NIC) acts as an agonist of this receptor. The present review aims to characterize the potential implication of the temperature circadian rhythm on the immune response, from molecular pathways to diseases. The uptake of these exosomes suppresses the growth of some cell types, but in general exosomes from FTS-treated cells enhance the recipient cell survival when compared to that of untreated cells. Salinity majorly hinders horizontal and vertical expansion in worldwide wheat production. These proteins form communication conduits with the extracellular space (hemichannels). The Journal of the History of Biology is devoted to the history of the biological sciences, with additional interest and concern in philosophical and social issues confronting biology. 2, Pomeranian Medical University, Szczecin, in northwestern Poland. Journal of Systems Biology Research (JSBR) journal is aimed at everyone working in the modelling and discovery of emergent properties in complex biological systems. International Journal of Applied Biology and Pharmaceutical Technology (ISSN: 0976-4550) is an Open Access peer-reviewed journal publishes articles quartely and supports researchers by publishing the highest quality scientific papers to promote all fields of biochemistry and molecular biology publishes articles in all aspects of biochemical processes, including the structure, function and dynamics of … Recently, it has been reported that heterogeneous ribonuclear protein M (HNRNPM) is a splicing factor associated with malignant tumors. This activity is most evident in populations with a high isoflavone dietary intake, essentially from soybean-based products. Exosomes are cell-derived nanovesicles, and lately, cancer-derived exosomes have been reported to carry KRAS protein, which contributes to the malignancy of many cancers. The MVC torques of the first and second–fifth MTPJs were measured at 0°, 15°, 30°, and 45° dorsiflexed positions of the MTPJs, and at 20° plantar-flexed, neutral, and 20° dorsiflexed positions of the ankle. Subscribe to receive issue release notifications and newsletters from MDPI journals, You can make submissions to other journals. Find out more here about BMC Biology features and editorial policy. The journal is abstracted and indexed in MEDLINE/PubMed. Part of About this journal. We use cookies on our website to ensure you get the best experience. Moreover, pancreatic cancer demonstrates a mechanism that allows it to survive in a hypovascular environment. This journal considers following types of papers (Link). Despite its ubiquity, the log-normal distribution concerning the elastic modulus of biological tissues does not have a clear explanation. The prognosis of pancreatic cancer is considerably worse than that of other cancers, as early detection of pancreatic cancer is difficult and due to its hypovascular environment, which involves low blood flow and a low supply of oxygen and nutrients. Biology (ISSN 2079-7737; CODEN: BBSIBX) is an international peer-reviewed open access journal of biological sciences published monthly online by MDPI. The assessment of welfare in aquatic animals is currently under debate, especially concerning those kept by humans. The evaluation of the drug effects on biofilm requires imaging methods that show the most detailed ultrastructural features of the biofilm. .. Abstracting and indexing without javascript enabled JMB ) provides high quality, comprehensive broad... For therapeutic targeting you agree to our Terms and Conditions, California Privacy Statement, Privacy Statement and policy. 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